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Gut microbiota - Mediterranean diet interactions in major depressive disorder (MDD): a review study
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Erfan Soroush   , Elaheh Salmeh , Ashkan Hajjafari , Seyed Ashkan Dehghani , Seyed Davar Siadat * |
| Department of Mycobacteriology and Pulmonary Research, Microbiology Research Center, Pasteur Institute of Iran, Tehran, Iran |
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Abstract: |
| Major depressive disorder is a growing debilitating disease that affects nearly 280 million people worldwide. The etiology of major depressive disorder is considered multifactorial, with diet and the microbiota of the gastrointestinal system being among the most significant factors. Nutritional interventions aimed at improving the diet and modifying the microbiota of the digestive system have significant effects on the recovery of depressed individuals, whose diets often lack vital nutrients and follow inappropriate patterns. In recent decades, the importance of the microbiota of the digestive system in maintaining human mental health and the various effects of diets on its composition have been considered. The Mediterranean diet, known for its health benefits, significantly impacts the gut-brain axis. Understanding these connections can guide the development of optimal nutritional strategies for improving both digestive and mental health of humans. This study aims to provide a broad and scientific review of research on the role of the digestive tract microbiota and the Mediterranean diet in major depressive disorder. |
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| Keywords: major depressive disorder, Mediterranean diet, microbiota, mental health, gut-brain axis |
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Type of Study: Research |
Subject:
General
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