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Investigating the effect of ethanolic and methanolic extracts of Hyssopus officinalis L on bacteria isolated from urinary and skin infections
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Fateme Nooraei *   , Ehsan Esan Nazifi |
| M.Sc in Microbiology, Department of Microbiology, Faculty of Science, University of Mazandaran, Babolsar |
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Abstract: |
Background and Objectives: Today, due to the relatively high prevalence of urinary and skin bacterial infections, the wide range of complications caused by these infections, as well as the occurrence of antibiotic resistance in many strains effective in these infections, the need to search for alternative drugs to treat these infections has increased. Therefore, the aim of this study was to investigate the antibacterial effects of methanolic and ethanolic extracts of Hyssopus officinalis L on Some bacterial strains were the cause of urinary and skin infections in laboratory conditions.
Materials and methods: extraction was done by maceration in methanol and ethanol solvents. And the antibacterial effects of the extract were investigated by disc diffusion test and determining the minimum inhibitory and the minimum bactericidal concentration (MIC/MBC) on seven pathogenic bacteria causing urinary and skin infections collected from Razi Hospital, Qaimshahr.
Results: Methanolic and ethanolic extracts of hyssop plant had antibacterial effects against the investigated bacteria. The antibacterial effects of the methanolic extract were higher than the ethanolic extract in most cases (except for Pseudomonas aeruginosa). Also, the antibacterial effect of hyssop plant extract on Gram-positive strains was more than on Gram-negative strains studied. The most sensitive bacteria to hyssop extract was Staphylococcus aureus isolated from skin infection and the most resistant bacteria was Escherichia coli isolated from urinary infection.
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| Keywords: Hyssopus officinalis L, Methanolic extract, ethanolic extract, antibacterial effects |
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Type of Study: Research |
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