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Gut microbiota in heart failure: A review of recent achievements
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Seyed Mohsen Mirhosseini   , Sepideh Djafari Naeini * |
| Cardiovascular research center, Shahid Beheshti university of medical sciences, Tehran, Iran |
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Abstract: |
In recent years, there has been particular attention to changes in the gut microbiome in patients with cardiovascular problems, especially heart failure. New and increasing information in this area, alongside the gut-cardiac axis theory which considers changes in gut microbiota as a potential factor in heart diseases such as atherosclerosis and hypertension, has led to new and extensive research aimed at understanding the possible pathophysiology of these diseases. The increase of pro-inflammatory bacteria and the decrease of anti-inflammatory microorganisms have been proposed as potential factors in these diseases, and efforts to better understand the pathogenesis of the disease and improve patients by modifying the gut microbiota continue. Although studies on the microbiota of the Iranian population have also been conducted in our country, there is still insufficient information regarding patients with heart problems, particularly heart failure.
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| Keywords: Heart failure, Gut microbiota, Indoxyl sulfate, heart transplantation |
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Type of Study: Review |
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